Hajos-Parrish reaction mechanism
نویسنده
چکیده
Organic chemist, born 1926 (Budapest, Hungary). Ph.D. (Technical Sciences) Technical University, Budapest, 1950. MS, Technical University, Budapest,1947. Assistant Professor Technical University, Budapest, Hungary 1948-1957. Research scientist Princeton University, Princeton, NJ 1957-1960; Hoffmann-La Roche, Inc. Nutley, NJ 1960-1970; University of Vermont, Burlington, VT 1972-1973; University of Toronto, Ontario, Canada 1973-1974; R.W.Johnson Pharmaceutical Research Institute, Raritan, NJ 1975-1990.
منابع مشابه
Evaluating beta-amino acids as enantioselective organocatalysts of the Hajos-Parrish-Eder-Sauer-Wiechert reaction.
A systematic study of the effect of substitution within the beta-amino acid framework indicates that both beta(2)- and beta(3)-amino acids catalyse the Hajos-Parrish-Eder-Sauer-Wiechert reaction with poor to reasonable levels of enantioselectivity. These results led to the evaluation of the conformationally constrained beta-amino acid (1R,2S)-cispentacin, which catalyses the Hajos-Parrish-Eder-...
متن کاملTotal synthesis of (+)-cyanthiwigin AC.
A 13-step synthesis of (+)-cyanthiwigin-AC (2) from (+)-Hajos-Parrish ketone derivative 8b and dimesylate 9c employing deconjugative spiro-bis-alkylation strategy is described. [reaction: see text].
متن کاملHajos–Parrish ketone: approaches toward C-ring precursors of 7-deoxytaxol
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متن کاملCombining multi-catalysis and multi-component systems for the development of one-pot asymmetric reactions: stereoselective synthesis of highly functionalized bicyclo[4.4.0]decane-1,6-diones.
We have developed a direct amine/acid-catalyzed stereoselective hydrogenation of a variety of Wieland-Miescher (W-M) ketones, Hajos-Parrish (H-P) ketones and their analogs with organic hydrides (Hantzsch esters) as the hydrogen source. This astonishingly simple and biomimetic approach was used to construct highly functionalized chiral bicyclo[4.4.0]decane-1,6-diones in a diastereoselective fash...
متن کاملFeed-forward inhibition underlies the propagation of cholinergically induced gamma oscillations from hippocampal CA3 to CA1 Norbert Hajos, Institute of Experimental Medicine of the Hungarian Academy of Sciences
http://jneurosci.msubmit.net JN-RM-3680-12R2 Feed-forward inhibition underlies the propagation of cholinergically induced gamma oscillations from hippocampal CA3 to CA1 Norbert Hajos, Institute of Experimental Medicine of the Hungarian Academy of Sciences Rita Zemankovics, Institute of Experimental Medicine Judit Veres, Institute of Experimental Medicine Iris Oren, Centre of Cognitive and Neuro...
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